Microsporidiosis generalizada por encephalitozoon sp en un paciente pediátrico con enfermedad de Bruton / Generalized microsporidiosis caused by encephalitozoon sp in a pediatric patient with Brutonïs disease

We present the case of a four year old boy with a history of repeated upper respiratory tract infections and pyoderma. He presented fever, seizures, inhability to talk, loss of swallowing, fine tremor in the upper extremities; positive bilateral Babinski reflex and quadriparesis. The diagnosis of Brutonïs disease and generalized microporidiosis was based on immunologic analysis, smear tests with chromotrope R2 stain and indirect immunofluorescense with monoclonal 3B6 antibody for Encephalitozoon species in samples of spinal fluid, bronchial and paranasal sinus aspirates and stool, which were all positive. The patient was treated with albendazol during 72 days; he left the hospital in a good condition, walking, talking and able to swallow. His laboratory test controls were negative; he is followed up in the outpatient department